Smoking Cessation:

Are you ready to quit?

Smokers interested in quitting are needed for a Clinical Trial

We need smokers to participate in a MRI study on smoking and craving in Menlo Park, CA.
Participants will be compensated for completion of the study.

• Participants must be between 21 and 50 years old, right handed, with a current smoking habit of at least 15 cigarettes per day over the past 3 years.
• You must be able to read and understand English.
• You will need to arrange transportation to our office in Menlo Park, CA for 8-13 visits.
• You will need to abstain from smoking for 12 hours before the first scan and quit smoking once you begin with nicotine replacement therapy (the patch). This will be verified with a breath test and urine analysis.
• Participation includes quitting smoking with use of nicotine replacement therapy (provided), completing questionnaires, and 3-9 scans in a full-body MRI machine, which may involving viewing your brain activity through virtual reality goggles and simultaneously using mental strategies to cognitively control your craving for nicotine.
• You cannot have a recent history of significant psychological, neurological, or substance abuse disorders other than nicotine dependence.
• You cannot participate if you have a sensitivity to noise, claustrophobia, tattoos on your head or face, implanted medical devices or dental work with posts. Women cannot be pregnant or breastfeeding or seeking to become pregnant, and this will be verified by a self-administered urine test.
• MRI does not involve ionizing radiation or X-rays.

To find out if you are eligible to participate go to www.donesmokingnow.com

Chronic Pain Clinical Trial

We are currently inviting chronic pain patients to participate in a study to investigate a treatment for pain that uses newly developed brain imaging methods to train participants to control their own brain activation. All participants in this study will receive a new form of cognitive training for controlling pain. A central goal of the study is to measure the impact of a new form of cognitive strategies for pain control on activations from brain regions involved in the experience of pain. Participants will be scanned using functional MRI while they employ cognitive strategies allowing the participant to view and mediate their brain activity.

Benefits to Participants

• Access a newly developed experimental brain imaging technology only available through this study

• Help with the research process of developing a potential future treatment for chronic pain


Eligibility Requirements

1. Men and Women, ages 21-55 years

2. Clinically diagnosed chronic pain. Verification from a medical Doctor is REQUIRED to participate. Some example of diagnoses include: CRPS, RSD, neuropathy, neuralgia, fibromyalgia, chronic low back pain or migraine.

3. No implanted medical devices that are not compatible with MRI (spinal cord stimulator/pump, pacemaker, surgical aneurysm clip, stents etc)

4. No recent history of severe psychiatric illness

5. Weight less than 220 lbs.

6. Able to be scanned in MRI without claustrophobia

7. No facial tattoos, non-removable metal implants, piercings, or extensive dental work.

8. Not pregnant or having fertility treatments

9. Able to read and understand English



Additional screening criteria for MRI safety may be required
Procedure

This is an experimental procedure and a controlled trial. We cannot and do not imply that this study will lead to a decrease in your pain.

Location

Participants MUST be able to attend 11 sessions in Menlo Park, CA. We reimburse for travel time within the Bay Area.

Compensation

In addition to extensive interaction with our knowledgeable research team, eligible participants will receive cash compensation for their participation (i.e. travel time, questionnaires, and all time in scanner). For your time and inconvenience, you will be paid $20/hour for the MRI portions of the study and $10/hour for all other times related to the study. Sponsor

The Principal Investigator on this research study is Dr. Christopher deCharms, PhD. This study is sponsored by Omneuron, Inc. and receives funding from the National Institutes of Health. Please contact via phone or email is you are interested in participating in the study. We will proceed with a phone screening to meet NIH study requirements and schedule upon successful completion.
Ella Laramee
Omneuron Research Associate (650) 585-5304 elaramee@omneuron.com